V. B. Grinevich1; S. P. Salikova1; O. V. Bystrova2; A. A. Vlasov1;
A. Osipov2; E. D. Zubrilova1
1S. M. Kirov Military Medical Academy, Saint Petersburg, Russia;
2International Analytical Centre IOC RAS, Moscow, Russia
Methods: Totally 42 patients were examined. The main Group 1 con- tained 31 patients with NYHA class III-IV CHF, the comparison Group 2 contained 11 patients with NYHA class I-II CHF. The amount of Hp in intestine’s mucus was determined by measurement of specific 3-hydroxystearic acid (3 h18) value in a blood using algorithm describedearlier. The Omega-3 Index was determined as the percent ratio of omega-3 unsaturated fatty acids (FA) to sum of other FA. All FA values were registered using gas-chromatography mass-spectrometry. Results were presented as average values±standard deviation. Relationships between parameters were determined by calculation of correlation co- efficients (r). Values were considered reliable at significance level P<.05.
Results: Presence of 3h18 was detected in 93.5% of Group 1 patients and in 82% of Group 2 patients. Amount of Hp in intestine’s mucus was 10.9±10.5 cells x105/gram in Group 1 and to 7.04±7.1 in Group 2. After in-patients treatment it has reduced to 5.4±4.3 in Group 1. The lowest Omega-3 Index was determined in Group 1 – 1.59±1, it increased after in-patients treatment up to 2.8±2.4, became compara- ble to one in Group 2 – 3.04±1.3. We determined the reliable negative correlation between Hp amount and Omega-3 Index (r=.37, P<.05). Conclusion: Presence of Hp may influence on pathogenesis of con- gestive heart failure. One of possible mechanisms is Hp’s effect on polyunsaturated FA metabolism.
Shirley
I’m extremely impressed together with your writing talents as smartly
as with the layout on your weblog. Is this a paid topic or did you modify it
your self? Either way stay up the nice quality writing, it is uncommon to peer a great weblog like this one these days.
Snipfeed!
Look at my web-site Instagram Auto follow